Privacy-preserving model learning on a blockchain network-of-networks.

ObjectiveTo facilitate clinical/genomic/biomedical research, constructing generalizable predictive models using cross-institutional methods while protecting privacy is imperative. However, state-of-the-art methods assume a "flattened" topology, while real-world research networks may consist of "network-of-networks" which can imply practical issues including training on small data for rare diseases/conditions, prioritizing locally trained models, and maintaining models for each level of the hierarchy. In this study, we focus on developing a hierarchical approach to inherit the benefits of the privacy-preserving methods, retain the advantages of adopting blockchain, and address practical concerns on a research network-of-networks.Materials and methodsWe propose a framework to combine level-wise model learning, blockchain-based model dissemination, and a novel hierarchical consensus algorithm for model ensemble. We developed an example implementation HierarchicalChain (hierarchical privacy-preserving modeling on blockchain), evaluated it on 3 healthcare/genomic datasets, as well as compared its predictive correctness, learning iteration, and execution time with a state-of-the-art method designed for flattened network topology.ResultsHierarchicalChain improves the predictive correctness for small training datasets and provides comparable correctness results with the competing method with higher learning iteration and similar per-iteration execution time, inherits the benefits of the privacy-preserving learning and advantages of blockchain technology, and immutable records models for each level.DiscussionHierarchicalChain is independent of the core privacy-preserving learning method, as well as of the underlying blockchain platform. Further studies are warranted for various types of network topology, complex data, and privacy concerns.ConclusionWe demonstrated the potential of utilizing the information from the hierarchical network-of-networks topology to improve prediction

Tunable Fano-Kondo resonance in side-coupled double quantum dot system

We study the interference between the Fano and Kondo effects in a side-coupled double-quantum- dot system where one of the quantum dots couples to conduction electron bath while the other dot only side-couples to the first dot via antiferromagnetic (AF) spin exchange coupling. We apply both the perturbative renormalization group (RG) and numerical renormalization group (NRG) approaches to study the effect of AF coupling on the Fano lineshape in the conduction leads. With particle-hole symmetry, the AF exchange coupling competes with the Kondo effect and leads to a local spin-singlet ground state for arbitrary small coupling, so called "two-stage Kondo effect". As a result, via NRG we find the spectral properties of the Fano lineshape in the tunneling density of states (TDOS) of conduction electron leads shows double dip-peak features at the energy scale around the Kondo temperature and the one much below it, corresponding to the two-stage Kondo effect; it also shows an universal scaling behavior at very low energies. We find the qualitative agreement between the NRG and the perturbative RG approach. Relevance of our work to the experiments is discussed.Comment: 7 pages, 7 figure

Decoherence and Recoherence in Model Quantum Systems

We discuss the various manifestations of quantum decoherence in the forms of dephasing, entanglement with the environment, and revelation of "which-path" information. As a specific example, we consider an electron interference experiment. The coupling of the coherent electrons to the quantized electromagnetic field illustrates all of these versions of decoherence. This decoherence has two equivalent interpretations, in terms of photon emission or in terms of Aharonov-Bohm phase fluctuations. We consider the case when the coherent electrons are coupled to photons in a squeezed vacuum state. The time-averaged result is increased decoherence. However, if only electrons which are emitted during selected periods are counted, the decoherence can be suppressed below the level for the photon vacuum. This is the phenomenon of recoherence. This effect is closely related to the quantum violations of the weak energy condition, and is restricted by similar inequalities. We give some estimates of the magnitude of the recoherence effect and discuss prospects for observing it in an electron interferometry experiment.Comment: 8 pages, 3 figures, talk presented at the 7th Friedmann Seminar, Joao Pessoa, Brazil, July 200

Impact of Teat Order on Feed Consumption in Swine from Birth to Nursery

A relationship between teat order and feed consumption has been assumed in pigs, but no study has looked at this exact relationship. Pigs were observed shortly after birth to be in either a cranial, middle, or caudal teat positon. Growth performance data and active and total plasma ghrelin concentrations were analyzed at birth, weaning, and at the end of the nursery stage of production to see if a relationship with teat order was present. Overall, no effect of teat order was found on average daily gain, average daily feed intake, gain-to-feed ratio, or body weight among pigs from each section of the udder. Differences did occur during certain stages of nursery, which can be of economic importance to producers. No difference was seen in active or total ghrelin levels or the active-to-total ghrelin ratio in relation to teat order, although there were differences in active and total ghrelin concentrations among the sampling days. Further research should be carried out to investigate what factors would contribute to this data contradicting previous inferences about the relationship of teat order and feed consumption in pigs

Spin-orbit torques acting upon a perpendicularly-magnetized Py layer

We show that Py, a commonly-used soft ferromagnetic material with weak anisotropy, can become perpendicularly-magnetized while depositing on Ta buffer layer with Hf or Zr insertion layers (ILs) and MgO capping layer. By using two different approaches, namely harmonic voltage measurement and hysteresis loop shift measurement, the dampinglike spin-orbit torque (DL-SOT) efficiencies from Ta/IL/Py/IL/MgO magnetic heterostructures with perpendicular magnetic anisotropy are characterized. We find that though Ta has a significant spin Hall effect, the DL-SOT efficiencies are small in systems with the Ta/Py interface compared to that obtained from the control sample with the traditional Ta/CoFeB interface. Our results indicate that the spin transparency for the Ta/Py interface is much less than that for the Ta/CoFeB interface, which might be related to the variation of spin mixing conductance for different interfaces